Description

Other name: N,N′,N′′-Tri-Boc-cyclen. 1,4,7-Tri-Boc-1,4,7,10-tetraazacyclododecane.

This product is a very important intermediate in the synthesis of the mono-N-functionalized DOTA-based ligands.

Ref.:

1) Biomedical Imaging: The Chemistry of Labels, Probes and Contrast Agents. Chapter 5.2

M. Braddock, Royal Society of Chemistry, 23.11.2011

2) A Tris(Zn^II−1,4,7,10-tetraazacyclododecane) Complex as a New Receptor for Phosphate Dianions in Aqueous Solution.

E. Kimura, S. Aoki T. Koike, M. Shiro, J. Am. Chem. Soc. 1997, 119, 3038-3076.

DOI: 10.1021/ja9640408