Description
2-(4-Isothiocyanatobenzyl)-1,4,7,10-tetraaza-1,4,7,10-tetra(2-carbamoylmethyl)cyclododecane.
This product is a modified DOTA-chelator containig isothiocyanate functional group and reactive towards various nucleophiles including amine and sulfhydryl groups on proteins.
Ref.:
1) Preparation of 212Pb-labeled monoclonal antibody using a novel 224Ra-based generator solution.
S. Westrøm, R,Generalov, T.B. Bønsdorff, R.H. Larsen Nucl. Med. Biol. 2017, 51, 1-9.
DOI: 10.1016/j.nucmedbio.2017.04.005.
