Synthesis and Analysis
Organic compounds for R&D purposes
Custom synthesis from 1 mg to 1 kg.
Purification up to specified level.
Synthetic route design and/or optimization based on your preconditions.
Stable isotope labeled compounds (D, 13C, 15N, and others). From deutero-methylated to labelled-prostaglandins and further.
Analysis and analytical method development.
Bioconjugation tools
Double-side functionalized compounds (maleimide, NHS ester, or other) with predefined spacers. For example, MBS, Sulfo-SIAB, SATA, etc. Fluorescent dyes: rhodamine, cyanine, FAM and others, modified with biocompatible conjugation groups (e.g. maleimide or NHS ester functional groups). Copper-free click chemistry reagents with cyclooctyne or azide based functionalities.
MRI contrast agents
Cyclen and NO2A based ligands and gadolinium chelate reagents with attached functionalities (e.g. NHS ester, Biotin, isothiocyanate, hormones, or pharmaceuticals).
Process optimization
Step-by-step screening
Reaction conditions optimization
Workup and isolation optimization
Mechanistic studies for in-depth process understanding
Identification and control of contaminants and impurities
Investigation of critical process parameters and applicable process parameter ranges
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