Description

{1,1’-(4,4,8,8-tetramethyl-4,8-diazaundecamethylene)bis[4-[(3-methylbenzo-1,3-oxazol-2-yl)methylidene]-1,4-dihydroquinolinium]tetraiodide}

Oxazole yellow dimer (OYD) can be used as a DNA stainig dye. When bound to DNA, the intensity of fluorescence increased more then 3000 times compared with an unbound reagent.

Can be used as a substitute for YOYO-1®

λex 458 nm; λem 564 nm (unbound)

Ref.:

1) Single‐molecule manipulation of double‐stranded DNA using optical tweezers: Interaction studies of DNA with RecA and YOYO‐1.

M.L. Bennink, O.D. Schärer, R. Kanaar, K. Sakata‐Sogawa, J.M. Schins, J.S. Kanger, B.G. de Grooth, J. Greve, Cytometry Part A. 1999, 36 (3), 200–208.

DOI:10.1002/(SICI)1097-0320(19990701)36:3<200::AID-CYTO9>3.0.CO;2-T