Description

Other names: Succinimidyl 4,4′-azipentanoate; 3-Methyl-3H-diazirine-3-propanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester; 2,5-Dioxopyrrolidin-1-yl 3-(3-Methyl-3H-diazirin-3-yl)propanoate.

This product contains amine-sensitive NHS group and photo-active diazirine group. It can be used for example in modification of arginine in native peptides for use in chemical probe development.

Ref.:

1) Direct Arginine Modification in Native Peptides and Application to Chemical Probe Development.

V. Grundler, K. Gademann, ACS Med. Chem. Lett. 2014, 5, 1290-1295.

DOI: 10.1021/ml5003508