Description
Other names: Biotin-PEG6-COOH. Biotin-PEG6-CO2H. Biotin-PEG6-carboxylic acid. 21-[D-(+)-Biotinylamino]-4,7,10,13,16,19-hexaoxaheneicosanoic acid.
Biotin-PEG-linker with end-carboxylic acid functionalty that is suitable for coupling to variuous amine functionalities, e.g. proteins, peptides or API molecules bearing free amino group.
The biotin motif is a popular linker used in biotechnology to conjugate proteins for biochemical assays. Both streptavidin and avidin bind with biotin with high affinity and specificity, thus allowing target fishing in biological objects.
Ref.:
1) Biotin-conjugated PEGylated porphyrin self-assembled nanoparticles co-targeting mitochondria and lysosomes for advanced chemo-photodynamic combination therapy.
B. Purushothaman, J. Choi, S. Park, J. Lee, A.A. Suganya Samson, S. Honga, J.M. Song, J. Mater. Chem. B 2019, 7, 65-79.
