Products – ChemiMart

R27 Dye

Dr. Patrick Durkin — Thu, 27 Nov 2025 10:12:35 +0000

R27 is a light stable benzothiazolium/pyridinium-based dye which finds application in the detection of double stranded DNA. This offers a more stable alternative to SYBR Green I and LC Green Plus, displaying almost no degradation of fluorescence after prolonged exposure (over 6 h) at temperatures up to 95 °C when used in a LightCycler® system for PCR.

λex 440 nm; λem 483-533 nm (dynamic mode)

Cyan 500 NHS Ester

Dr. Patrick Durkin — Thu, 25 Jan 2024 11:17:02 +0000

Cyan 500 NHS Ester is a moderately hydrophilic amine-reactive fluorescent marker. This compound is used to label oligonucleotides, peptides, and other biomolecules bearing an amino-functionality, that can be detected when excited at 450 nm.

λex 450 nm; λem 495 nm

1-Undecanethiol

Dr. Patrick Durkin — Tue, 17 May 2022 08:07:20 +0000

1-Undecanethiol can be used to produce hydrophobic self-assembled monolayers, and also reduce non-specific protein adsorption mechanisms.

Synonym(s):

N-UNDECYL MERCAPTAN;UNDECANETHIOL;undecane-1-thiol;Undecyl mercaptan;1-UNDECANETHIOL;1-UNDECANETHIOL 95+%;1-Mercaptoundecane;1-Undecanethiol,1-UDT, 11-Mercapto-1-undecanol, Undecyl Mercaptan

References:

Simple and rapid mercury ion selective electrode based on 1-undecanethiol assembled Au substrate and its recognition mechanism.

Li et al. Mater. Sci. Eng. C. Mater. Biol. Appl. 2017 Mar 1;72:26-33.

Bis(1-butylpentyl)decane-1,10-diyl diglutarate

Dr. Patrick Durkin — Fri, 25 Mar 2022 10:41:22 +0000

Bis(1-butylpentyl)decane-1,10-diyl diglutarate is a neutral ionophore that can be used to prepare sodium optode membranes. These can be used to measure total sodium concentration in human blood plasma. This can also be used as a nitrite-selective membrane electrode, for the determination of NAD(P)H coenzymes.

Synonym(s):

5,30-Dibutyl-6,12,23,29-tetraoxatetratriacontane-7,11,24,28-tetrane, ETH 469

References:

Ion-selective electrodes and their clinical application in the continuous ion monitoring.

W Simon et al. Annals of the New York Academy of Sciences, 428, 279-285 (1984-01-01)

Potentiometric Determination of NAD(P)H Coenzymes Using a Nitrite-Selective Membrane Electrode and a Nitrate Reductase Enzyme and the Application to Glucose Assay in Human Serum, Katsu, T., et al. Analytical Sciences, 15, 135-139 (1999)

Acridine Orange Hydrochloride Salt, extra pure

Dr. Patrick Durkin — Wed, 12 Jan 2022 09:53:54 +0000

Acirdine Orange is a cell permeable staining dye that intercalates with DNA.

λex 460 nm; λem 650 nm

Sodium 4-(adamantan-1-ylamino)-4-oxobutane-1-sulfonate

mzaug — Wed, 09 Dec 2020 16:06:47 +0000

2-(2-Cyclooctyn-1-yloxy)acetic acid

mzaug — Wed, 09 Dec 2020 15:47:16 +0000

Building block for the strain-promoted copper-free click chemistry ligation techniques. Can be attached to the protein, peptide or small molecule via amide or ester bond.

Ref.:

1) Enabling the Multigram Synthesis of (2-Cyclooctyn-1-yloxy)acetic Acid.

M. Burk, S. Rothstein, P. Dubé, Org. Process Res. Dev. 2018, 22, 108-110.

DOI: 10.1021/acs.oprd.7b00275

endo-BCN-OH

mzaug — Wed, 09 Dec 2020 15:44:25 +0000

Other names: (1α,8α,9β)-Bicyclo[6.1.0]non-4-yne-9-methanol.

Building block for the strain-promoted copper-free click chemistry ligation techniques. Can be attached to the protein, peptide or small molecule via ether or ester bond. The hydroxyl functionality can also be used as a leaving group in nucleophilic substitution reactions.

Ref.:

1) Bicyclononynes: New Ring-Strained Alkynes for Bioorthogonal Labeling.

J. Dommerholt, S. Schmidt, R. Temming, L. J. A. Hendriks, F. P. J. T. Rutjes, J. C. M. van Hest, D. J. Lefeber, P. Friedl, F. L. van Delft, Synfacts 2011, 2, 0157-0157.

DOI: 10.1055/s-0030-1259250

5,6-Dihydro-11,12-didehydrodibenzo[a,e]cyclo-octen-5-ol

mzaug — Wed, 09 Dec 2020 15:42:09 +0000

Other name: 3-Hydroxy-1,2:5,6-dibenzocyclooct-7-yne.

Building block for the strain-promoted copper-free click chemistry ligation techniques. Can be attached to the protein, peptide or small molecule via ether or ester bond.

Ref.:

1) The one-pot nonhydrolysis Staudinger reaction and Staudinger or SPAAC ligation.

L. Cheng, X. Kang, D. Wang, Y. Gao, L. Yi, Z. Xi, Org. Biomol. Chem. 2019, 17, 5675-5679.

DOI: 10.1039/C9OB00528E

Biotin-PEG-COOH

mzaug — Wed, 09 Dec 2020 15:37:54 +0000

Other names: Biotin-PEG6-COOH. Biotin-PEG6-CO₂H. Biotin-PEG6-carboxylic acid. 21-[D-(+)-Biotinylamino]-4,7,10,13,16,19-hexaoxaheneicosanoic acid.

Biotin-PEG-linker with end-carboxylic acid functionalty that is suitable for coupling to variuous amine functionalities, e.g. proteins, peptides or API molecules bearing free amino group.

The biotin motif is a popular linker used in biotechnology to conjugate proteins for biochemical assays. Both streptavidin and avidin bind with biotin with high affinity and specificity, thus allowing target fishing in biological objects.

Ref.:

1) Biotin-conjugated PEGylated porphyrin self-assembled nanoparticles co-targeting mitochondria and lysosomes for advanced chemo-photodynamic combination therapy.

B. Purushothaman, J. Choi, S. Park, J. Lee, A.A. Suganya Samson, S. Honga, J.M. Song, J. Mater. Chem. B 2019, 7, 65-79.